Presenter: Prof Lehana Thabane, Professor/Associate Chair, Clinical Epidemiology and Biostatistics;
Associate Member, Departments of Anesthesia/Pediatrics, McMaster University
Abstract: Knowledge translation (KT) involves implementation of evidence-based guidelines into practice to improve the process of care and consequently health outcomes for patients. Pragmatic trials are used in KT to provide patients, healthcare providers and policy-makers with reliable and relevant information to optimize healthcare decisions. However, they have been criticized as “less perfect experiments” than explanatory trials; as creating “problems” by allowing non-compliance and cross-overs; creating “bias” by lack of blinding; requiring “large sample sizes” and “sacrificing internal validity to achieve generalizability”. In this presentation, I will discuss whether or not these criticisms hold merit, and I will use the cardiovascular health awareness program [CHAP] trial—a community randomization pragmatic trial designed to assess whether offering a highly organized, community-based CHAP intervention compared to usual care can reduce cardiovascular disease (CVD) related outcomes—to illustrate how to address the issues.
When: Monday October 28th, 2013
6-7 pm seminar
7 pm dinner (optional, but registration required)
Where: Room 7-605, Princess Margaret Hospital, 610 University Avenue
Cost: Seminar – free
Dinner – $15 (students $5)
To attend, please RSVP by or on Friday the 25th of October:
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*** Purdue Pharma Canada ***
*** McDougall Scientific ***
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TABA executive:
Ruth Croxford
Marguerite Ennis
Lorinda Simms
Eric Cai
Angelo Canty