2010/11 session 2011-03-29 seminar

The Applied Biostatistics Association (TABA) invites you to a seminar and dinner:Speaker: Eshetu Atenafu, Biostatistics Department, Princess Margaret Hospital Cancer Program / UHN

Topic: Relative Importance of Variables in Developing and Validating Predictive Models

Abstract:  Multiple regression models are used in a wide range of scientific disciplines and automated model selection procedures are frequently used to identify independent predictors. However, determination and relative importance of these potential predictors and validating the fitted models for their stability, predictive accuracy and generalizability are often overlooked or not done thoroughly. In this presentation, two proposals, bootstrapping and random split of data, are presented to compare strategies for ordering potential predictors according to their relative importance with respect to model stability and generalizability. Additional approach will be proposed based on relative increase in percentage of explained variation and area under the Receiver Operating Characteristic (ROC) curve for developing models where variables from our ordered list enter the model according to their importance. A data set aimed at identifying predictors of prostate cancer penetration will be used for illustrative purposes.
When: Tuesday, March 29, 2011
6-7 pm seminar
7 pm dinner (optional, but pre-registration required)

Where: Room 7-605, Princess Margaret Hospital, 610 University Avenue

Cost: Seminar – free
Dinner – $15  (students $5)

Please RSVP to Tina Haller at taba.exec@gmail.com by Thursday March 24th if you plan to attend the seminar or the dinner (see dinner cancellation policy below).
If you plan to attend the dinner, please mail a cheque payable to TABA to
Tina Haller
xxxxxxxxxxxx
xxxxxxxxxx
xxx xxx

If you have signed up for dinner, and have to cancel, we request a 48 hour notice.  Otherwise, TABA does have to pay for the dinner, and we will have to pass the cost back onto you.

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TABA seminars are made possible thanks in part to generous donations from Everest, Amgen, McDougall Scientific Ltd and Purdue Pharma. If you would like to see your company name here as a sponsor, please contact Tina Haller or Ruth Croxford (taba.exec@gmail.com).
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TABA excutive:
Ruth Croxford, President
Reid Robson, Vice President
Tina Haller, Treasurer
Lorinda Simms, Secretary
Marguerite Ennis, Secretary

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